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NABP North American Pharmacist Licensure Examination Sample Questions (Q100-Q105):
NEW QUESTION # 100
An 18-year-old female is referred to a dermatologist for treatment of severe acne vulgaris. The dermatologist wants to start her on tetracycline.
What test should the patient have prior to starting treatment?
- A. Complete blood count
- B. Chest X-ray
- C. Pregnancy test
- D. Liver function tests
- E. Creatine kinase
Answer: C
Explanation:
Explanation
Pregnancy test. Tetracyclines are effective in the treatment of severe cases of acne. They are however teratogenic. As such, it is imperative to make sure female patients are not pregnant prior to starting this medication. In many instances patients are started on concurrent birth control to mitigate this risk even further.
A chest x-ray (B) is an important exam to obtain prior to starting drugs which have pulmonary toxicity as a side effect such as amiodarone. A complete blood count (C) would be useful prior to starting a medication that causes anemia, such as immunosuppressive and chemotherapeutic agents. Liver function tests (D) are important to establish as a baseline prior to starting anti-mycobacterial agents. Creatine kinase levels (E) are used to establish as a baseline prior to starting statins.
NEW QUESTION # 101
After talking to the physician you find out her labs. Her labs reveled albumin level of 2.1gm/dL, calcium of
7.8mg/dL, glucose 120mg/dL , sodium 138 mmol/L, phenytoin level of 17.8.
Based on the given data which of the following best interprets phenytoin concentration?
- A. Phenytoin level need to be repeated
- B. Phenytoin level is too high
- C. Phenytoin level is with normal limits
- D. Phenytoin level is too low
- E. Phenytoin level cannot be determined
Answer: B
Explanation:
Explanation
Corrected phenytoin (mg/L) = Observed phenytoin (mg/L) / (0.2 x albumin [g/dL]) + 0.1 = 17.8 / (0.2 x 2.1) +
0.1 = 17.8 / 0.42 + 0.1 = 42.48mg/L phenytoin level is high. Normal therapeutic range is: 10-20mg/dL
NEW QUESTION # 102
What vitamin should the a patient receive to avoid Wernicke- Korsakoff syndrome?
- A. Nicotinic Acid
- B. Folic Acid
- C. Magnesium
- D. Cyanocobalamin
- E. Thiamine
Answer: E
Explanation:
Explanation
Thiamine should be administered to prevent Wernicke's encephalopathy.
NEW QUESTION # 103
Which of the following is a side effect of valproic acid?
- A. Pancreatitis
- B. Kidney stones
- C. Euphoria
- D. Gingival hyperplasia
- E. Weight loss
Answer: A
Explanation:
Explanation
Pancreatitis is one of the most serious adverse effects that can be caused by valproic acid. Gingival hyperplasia is a side effect of Phenytoin. Kidney stones and weight loss can be a side effect of zonisamide or topiramate.
NEW QUESTION # 104
Which of the following is dichotomous variable?
- A. NYHA I-IV
- B. Pain yes/ Pain no
- C. Sex
- D. Grade of Breast Cancer
- E. alive / dead
Answer: E
Explanation:
Dichotomous data is considered categorical data that only has two categories, or two answer choices. All 3 answer choices have only 2 categories: sex has male or female, pain is yes or no, and alive or dead is only two options also.
Reference:
http://www.bmj.com/about-bmj/resources-readers/publications/statistics-square-one
NEW QUESTION # 105
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